Microsoft has made its next set of layoffs, continuing the downsizing announced in July. Some 2,100 jobs have been cut worldwide, with 747 of those in the company’s home state of Washington.

CEO Satya Nadella plans to shrink the company by about 18,000 people overall, with 12,500 of these coming from the 25,000 staff that came with the newly acquired Nokia handset business. In the first round of cuts in July, 13,000 jobs were lost. With today’s cuts, that leaves another 2,900 positions that Microsoft wants to eliminate.

One victim is Microsoft Research’s Silicon Valley lab, reports Mary Jo Foley at ZDNet. The lab, which focused on distributed computing and large-scale systems, will be closing on Friday. Microsoft has said that some researchers will be offered positions at other labs.